Description

This panel includes the 16.5-kb mitochondrial genome (mtDNA) containing 37 genes, all of which are essential for normal mitochondrial function, which is passed down maternally from mother to child. This test is used to trace maternal ancestry, identify genetic mutations linked to certain inherited mitochondrial disorders, and investigate conditions related to energy production defects in the body, as mitochondria play a critical role in cellular energy metabolism. Unlike nuclear DNA, mtDNA is inherited only from the mother, making it useful for studying maternal lineage and diagnosing diseases related to mitochondrial dysfunction. This test includes mitochondrial genes. Nuclear mitochondrial genes are not included. ≥5% mitochondrial heteroplasmy can be confidently detected. By encompassing the entire genome, WGS provides a complete genetic profile, aiding in diagnosis, treatment planning, and understanding of complex traits or diseases.

4-6 weeks

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