What are the conditions that NIPT, NIPT Twins, and NIPT Advanced can detect?

Trisomies

Sex Chromosome Aneuploidies

Trisomy 21 (Down syndrome)

Sensitivity  >99.9%         

Specificity   99.9%

X0 (Turner syndrome)

Concordance with cytogenetic results  90.5 %

Trisomy 18 (Edwards syndrome)

Sensitivity  >99.9%         

Specificity   99.9%

XXX (Triple X syndrome)

Concordance with cytogenetic results   100.0 %

Trisomy 13 (Patau syndrome)

Sensitivity  >99.9%         

Specificity   99.9%

XXY (Klinefelter syndrome)

Concordance with cytogenetic results  100.0 %

 

XYY (Jacobs syndrome)

Concordance with cytogenetic results   91.7 %

 

Comprehensive view of the fetal genome

  • Screens entire fetal genome and not just trisomies in chromosomes 21, 18, and 13
 

Sensitivity and specificity for aneuploidy detected samples compared with published validation metrics

 

The BION NIPT test is performed with the latest available sequencing technology from Illumina with the CE/IVD standard, in addition:

  • High sensitivity/specificity for low false positive and negative
  • It has an accuracy of over 99%.
  • Pre and post-test genetic counseling for all